Human GNB1 activation kit by CRISPRa

CAT#: GA101854

GNB1 CRISPRa kit - CRISPR gene activation of human G protein subunit beta 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GNB1
• Locus ID: 2782
• Kit Components:

  GA101854G1, GNB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101854G2, GNB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101854G3, GNB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282538, NM_001282539, NM_002074
• Synonyms: MRD42
• Summary: 'Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]'