Human GNG5 activation kit by CRISPRa

CAT#: GA101859

GNG5 CRISPRa kit - CRISPR gene activation of human G protein subunit gamma 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GNG5
• Locus ID: 2787
• Kit Components:

  GA101859G1, GNG5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101859G2, GNG5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101859G3, GNG5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005274
• Synonyms: FLJ92393
• Summary: 'G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010]'