Human GM130 (GOLGA2) activation kit by CRISPRa

CAT#: GA101871

GOLGA2 CRISPRa kit - CRISPR gene activation of human golgin A2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GOLGA2
• Locus ID: 2801
• Kit Components:

  GA101871G1, GM130 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101871G2, GM130 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101871G3, GM130 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004486, NM_001366244, NM_001366246
• Synonyms: GM130
• Summary: 'The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010]'