Human Aspartate Aminotransferase (GOT1) activation kit by CRISPRa

CAT#: GA101875

GOT1 CRISPRa kit - CRISPR gene activation of human glutamic-oxaloacetic transaminase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GOT1
• Locus ID: 2805
• Kit Components:

  GA101875G1, Aspartate Aminotransferase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101875G2, Aspartate Aminotransferase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101875G3, Aspartate Aminotransferase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002079
• Synonyms: ASTQTL1; cAspAT; cCAT; GIG18
• Summary: 'Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. [provided by RefSeq, Jul 2008]'