Human Glycoprotein 2 (GP2) activation kit by CRISPRa

CAT#: GA101880

GP2 CRISPRa kit - CRISPR gene activation of human glycoprotein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GP2
• Locus ID: 2813
• Kit Components:

  GA101880G1, Glycoprotein 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101880G2, Glycoprotein 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101880G3, Glycoprotein 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001007240, NM_001007241, NM_001007242, NM_001502
• Synonyms: ZAP75
• Summary: 'This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]'