Human GPR3 activation kit by CRISPRa

CAT#: GA101892

GPR3 CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPR3
• Locus ID: 2827
• Kit Components:

  GA101892G1, GPR3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101892G2, GPR3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101892G3, GPR3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005281
• Synonyms: ACCA
• Summary: 'This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease. [provided by RefSeq, Oct 2012]'