Human GRB7 activation kit by CRISPRa

CAT#: GA101942

GRB7 CRISPRa kit - CRISPR gene activation of human growth factor receptor bound protein 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GRB7
• Locus ID: 2886
• Kit Components:

  GA101942G1, GRB7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101942G2, GRB7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101942G3, GRB7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001030002, NM_001242442, NM_001242443, NM_001330207, NM_005310
• Synonyms: growth factor receptor-bound protein 7; OTTHUMP00000164352
• Summary: 'The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]'