Human GTF2A1 activation kit by CRISPRa

CAT#: GA102002

GTF2A1 CRISPRa kit - CRISPR gene activation of human general transcription factor IIA subunit 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GTF2A1
• Locus ID: 2957
• Kit Components:

  GA102002G1, GTF2A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102002G2, GTF2A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102002G3, GTF2A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278940, NM_015859, NM_201595, NR_048573
• Synonyms: TF2A1; TFIIA; TFIIA-42; TFIIAL
• Summary: 'Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]'