Human GUCY2F activation kit by CRISPRa

CAT#: GA102026

GUCY2F CRISPRa kit - CRISPR gene activation of human guanylate cyclase 2F, retinal

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GUCY2F
• Locus ID: 2986
• Kit Components:

  GA102026G1, GUCY2F gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102026G2, GUCY2F gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102026G3, GUCY2F gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001522
• Synonyms: CYGF; GC-F; GUC2DL; GUC2F; RETGC-2; ROS-GC2
• Summary: 'The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa. [provided by RefSeq, Dec 2008]'