Human beta glucuronidase (GUSB) activation kit by CRISPRa

CAT#: GA102029

GUSB CRISPRa kit - CRISPR gene activation of human glucuronidase beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GUSB
• Locus ID: 2990
• Kit Components:

  GA102029G1, beta glucuronidase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102029G2, beta glucuronidase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102029G3, beta glucuronidase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000181, NM_001284290, NM_001293104, NM_001293105, NR_120531
• Synonyms: BG; MPS7
• Summary: 'This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.[provided by RefSeq, May 2014]'