Human Glycophorin C (GYPC) activation kit by CRISPRa

CAT#: GA102033

GYPC CRISPRa kit - CRISPR gene activation of human glycophorin C (Gerbich blood group)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GYPC
• Locus ID: 2995
• Kit Components:

  GA102033G1, Glycophorin C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102033G2, Glycophorin C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102033G3, Glycophorin C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256584, NM_002101, NM_016815
• Synonyms: CD236; CD236R; GE; GPC; GPD; GYPD; PAS-2
• Summary: 'Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]'