Human HAS3 activation kit by CRISPRa

CAT#: GA102068

HAS3 CRISPRa kit - CRISPR gene activation of human hyaluronan synthase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HAS3
• Locus ID: 3038
• Kit Components:

  GA102068G1, HAS3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102068G2, HAS3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102068G3, HAS3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199280, NM_005329, NM_138612
• Summary: 'The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]'