Human HIC1 activation kit by CRISPRa

CAT#: GA102106

HIC1 CRISPRa kit - CRISPR gene activation of human HIC ZBTB transcriptional repressor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HIC1
• Locus ID: 3090
• Kit Components:

  GA102106G1, HIC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102106G2, HIC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102106G3, HIC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001098202, NM_006497
• Synonyms: hic-1; ZBTB29; ZNF901
• Summary: 'This gene functions as a growth regulatory and tumor repressor gene. Hypermethylation or deletion of the region of this gene have been associated with tumors and the contiguous-gene syndrome, Miller-Dieker syndrome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2010]'