Human HMBS activation kit by CRISPRa

CAT#: GA102144

HMBS CRISPRa kit - CRISPR gene activation of human hydroxymethylbilane synthase

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

Product Images

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol HMBS
Locus ID 3145
Kit Components

GA102144G1, HMBS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102144G2, HMBS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102144G3, HMBS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000190, NM_001024382, NM_001258208, NM_001258209
Synonyms PBG-D; PBGD; PORC; UPS
Summary 'This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.