Human HMGN2 activation kit by CRISPRa

CAT#: GA102149

HMGN2 CRISPRa kit - CRISPR gene activation of human high mobility group nucleosomal binding domain 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HMGN2
• Locus ID: 3151
• Kit Components:

  GA102149G1, HMGN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102149G2, HMGN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102149G3, HMGN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005517
• Synonyms: HMG17
• Summary: 'The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014]'