Human Heme oxygenase 2 (HMOX2) activation kit by CRISPRa

CAT#: GA102157

HMOX2 CRISPRa kit - CRISPR gene activation of human heme oxygenase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HMOX2
• Locus ID: 3163
• Kit Components:

  GA102157G1, Heme oxygenase 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102157G2, Heme oxygenase 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102157G3, Heme oxygenase 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001127204, NM_001127205, NM_001127206, NM_001286267, NM_001286268, NM_001286269, NM_001286270, NM_001286271, NM_002134
• Synonyms: HO-2
• Summary: 'Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]'