Human HOXA9 activation kit by CRISPRa

CAT#: GA102190

HOXA9 CRISPRa kit - CRISPR gene activation of human homeobox A9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HOXA9
• Locus ID: 3205
• Kit Components:

  GA102190G1, HOXA9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102190G2, HOXA9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102190G3, HOXA9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002142, NM_152739
• Synonyms: ABD-B; homeo box A9; homeobox A9; homeobox protein HOXA9; homeodomain protein HOXA9; HOX1; HOX1, ABD-B, HOX1G, HOX1.7, MGC1934; HOX1.7; HOX1G; MGC1934
• Summary: 'In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.[provided by RefSeq, Mar 2011]'