Human ERAS activation kit by CRISPRa

CAT#: GA102232

ERAS CRISPRa kit - CRISPR gene activation of human ES cell expressed Ras

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ERAS
• Locus ID: 3266
• Kit Components:

  GA102232G1, ERAS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102232G2, ERAS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102232G3, ERAS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_181532
• Synonyms: HRAS2; HRASP
• Summary: 'This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012]'