Human HES1 activation kit by CRISPRa

CAT#: GA102241

HES1 CRISPRa kit - CRISPR gene activation of human hes family bHLH transcription factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HES1
• Locus ID: 3280
• Kit Components:

  GA102241G1, HES1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102241G2, HES1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102241G3, HES1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005524
• Synonyms: bHLHb39; HES-1; HHL; HRY
• Summary: 'This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. [provided by RefSeq, Jul 2008]'