Human HSD17B3 activation kit by CRISPRa

CAT#: GA102248

HSD17B3 CRISPRa kit - CRISPR gene activation of human hydroxysteroid 17-beta dehydrogenase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HSD17B3
• Locus ID: 3293
• Kit Components:

  GA102248G1, HSD17B3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102248G2, HSD17B3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102248G3, HSD17B3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000197
• Synonyms: EDH17B3; SDR12C2
• Summary: 'This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]'