Human HSP90AB1 activation kit by CRISPRa

CAT#: GA102269

HSP90AB1 CRISPRa kit - CRISPR gene activation of human heat shock protein 90 alpha family class B member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HSP90AB1
• Locus ID: 3326
• Kit Components:

  GA102269G1, HSP90AB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102269G2, HSP90AB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102269G3, HSP90AB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271969, NM_001271970, NM_001271971, NM_001271972, NM_007355, NR_073528
• Synonyms: D6S182; HSP84; HSP90B; HSPC2; HSPCB
• Summary: 'This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Dec 2012]'