Human Hsp60 (HSPD1) activation kit by CRISPRa

CAT#: GA102270

HSPD1 CRISPRa kit - CRISPR gene activation of human heat shock protein family D (Hsp60) member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HSPD1
• Locus ID: 3329
• Kit Components:

  GA102270G1, Hsp60 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102270G2, Hsp60 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102270G3, Hsp60 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002156, NM_199440
• Synonyms: CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13
• Summary: 'This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]'