Human Cpn10 (HSPE1) activation kit by CRISPRa

CAT#: GA102271

HSPE1 CRISPRa kit - CRISPR gene activation of human heat shock protein family E (Hsp10) member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HSPE1
• Locus ID: 3336
• Kit Components:

  GA102271G1, Cpn10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102271G2, Cpn10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102271G3, Cpn10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002157
• Synonyms: CPN10; EPF; GROES; HSP10
• Summary: 'This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011]'