Human HTR1B activation kit by CRISPRa

CAT#: GA102280

HTR1B CRISPRa kit - CRISPR gene activation of human 5-hydroxytryptamine receptor 1B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HTR1B
• Locus ID: 3351
• Kit Components:

  GA102280G1, HTR1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102280G2, HTR1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102280G3, HTR1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000863
• Synonyms: 5-HT1B; 5-HT1DB; HTR1D2; HTR1DB; S12
• Summary: 'The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs. [provided by RefSeq, Nov 2015]'