Human 5HT4 Receptor (HTR4) activation kit by CRISPRa

CAT#: GA102288

HTR4 CRISPRa kit - CRISPR gene activation of human 5-hydroxytryptamine receptor 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HTR4
• Locus ID: 3360
• Kit Components:

  GA102288G1, 5HT4 Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102288G2, 5HT4 Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102288G3, 5HT4 Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000870, NM_001040169, NM_001040171, NM_001040172, NM_001040173, NM_001040174, NM_001286410, NM_199453, NR_104445
• Synonyms: 5-HT4; 5-HT4R
• Summary: 'This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]'