Human Amylin (IAPP) activation kit by CRISPRa

CAT#: GA102295

IAPP CRISPRa kit - CRISPR gene activation of human islet amyloid polypeptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IAPP
• Locus ID: 3375
• Kit Components:

  GA102295G1, Amylin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102295G2, Amylin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102295G3, Amylin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000415, NM_001329201
• Synonyms: DAP; IAP
• Summary: 'This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016]'