Human IFNA13 (IFNA1) activation kit by CRISPRa

CAT#: GA102326

IFNA1 CRISPRa kit - CRISPR gene activation of human interferon alpha 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IFNA1
• Locus ID: 3439
• Kit Components:

  GA102326G1, IFNA13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102326G2, IFNA13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102326G3, IFNA13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024013
• Synonyms: IFL; IFN; IFN-ALPHA; IFN-alphaD; IFNA13; IFNA@
• Summary: 'This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia. [provided by RefSeq, Aug 2020]'