Human Interferon gamma (IFNG) activation kit by CRISPRa

CAT#: GA102342

IFNG CRISPRa kit - CRISPR gene activation of human interferon gamma

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IFNG
• Locus ID: 3458
• Kit Components:

  GA102342G1, Interferon gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102342G2, Interferon gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102342G3, Interferon gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000619
• Synonyms: IFG; IFI
• Summary: 'This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]'