Human IFNGR1 activation kit by CRISPRa

CAT#: GA102343

IFNGR1 CRISPRa kit - CRISPR gene activation of human interferon gamma receptor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IFNGR1
• Locus ID: 3459
• Kit Components:

  GA102343G1, IFNGR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102343G2, IFNGR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102343G3, IFNGR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000416, NM_001363527, NM_001363526
• Synonyms: CD119; IFNGR; IMD27A; IMD27B
• Summary: 'This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]'