Human IGF1 activation kit by CRISPRa

CAT#: GA102348

IGF1 CRISPRa kit - CRISPR gene activation of human insulin like growth factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IGF1
• Locus ID: 3479
• Kit Components:

  GA102348G1, IGF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102348G2, IGF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102348G3, IGF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000618, NM_001111283, NM_001111284, NM_001111285
• Synonyms: IGF-I; IGFI; MGF
• Summary: 'The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]'