Human IGFBP4 activation kit by CRISPRa

CAT#: GA102356

IGFBP4 CRISPRa kit - CRISPR gene activation of human insulin like growth factor binding protein 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IGFBP4
• Locus ID: 3487
• Kit Components:

  GA102356G1, IGFBP4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102356G2, IGFBP4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102356G3, IGFBP4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001552
• Synonyms: BP-4; HT29-IGFBP; IBP4; IGFBP-4
• Summary: 'This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]'