Human IL1 Receptor I (IL1R1) activation kit by CRISPRa

CAT#: GA102373

IL1R1 CRISPRa kit - CRISPR gene activation of human interleukin 1 receptor type 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL1R1
• Locus ID: 3554
• Kit Components:

  GA102373G1, IL1 Receptor I gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102373G2, IL1 Receptor I gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102373G3, IL1 Receptor I gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000877, NM_001288706, NM_001320978, NM_001320980, NM_001320981, NM_001320982, NM_001320983, NM_001320984, NM_001320985, NM_001320986
• Synonyms: CD121A; D2S1473; IL-1R-alpha; IL1R; IL1RA; P80
• Summary: 'This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013]'