Human IL1RAP activation kit by CRISPRa

CAT#: GA102374

IL1RAP CRISPRa kit - CRISPR gene activation of human interleukin 1 receptor accessory protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL1RAP
• Locus ID: 3556
• Kit Components:

  GA102374G1, IL1RAP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102374G2, IL1RAP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102374G3, IL1RAP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001167928, NM_001167929, NM_001167930, NM_001167931, NM_002182, NM_134470, NM_001364879, NM_001364880, NR_157353, NM_001364881, NR_157352
• Synonyms: C3orf13; IL-1RAcP; IL1R3
• Summary: 'This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]'