Human IL10RB activation kit by CRISPRa

CAT#: GA102398

IL10RB CRISPRa kit - CRISPR gene activation of human interleukin 10 receptor subunit beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL10RB
• Locus ID: 3588
• Kit Components:

  GA102398G1, IL10RB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102398G2, IL10RB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102398G3, IL10RB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000628
• Synonyms: CDW210B; CRF2-4; CRFB4; D21S58; D21S66; IL-10R2
• Summary: 'The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. [provided by RefSeq, Jul 2008]'