Human IL13 receptor alpha 1 (IL13RA1) activation kit by CRISPRa

CAT#: GA102406

IL13RA1 CRISPRa kit - CRISPR gene activation of human interleukin 13 receptor subunit alpha 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL13RA1
• Locus ID: 3597
• Kit Components:

  GA102406G1, IL13 receptor alpha 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102406G2, IL13 receptor alpha 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102406G3, IL13 receptor alpha 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001560
• Synonyms: CD213A1; CT19; IL-13Ra; NR4
• Summary: 'The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]'