Human IRAK (IRAK1) activation kit by CRISPRa

CAT#: GA102448

IRAK1 CRISPRa kit - CRISPR gene activation of human interleukin 1 receptor associated kinase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IRAK1
• Locus ID: 3654
• Kit Components:

  GA102448G1, IRAK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102448G2, IRAK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102448G3, IRAK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001025242, NM_001025243, NM_001569
• Synonyms: IRAK; pelle
• Summary: 'This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'