Human IRF7 activation kit by CRISPRa

CAT#: GA102458

IRF7 CRISPRa kit - CRISPR gene activation of human interferon regulatory factor 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IRF7
• Locus ID: 3665
• Kit Components:

  GA102458G1, IRF7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102458G2, IRF7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102458G3, IRF7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001572, NM_004029, NM_004030, NM_004031
• Synonyms: IMD39; IRF-7H; IRF7A; IRF7B; IRF7C; IRF7H
• Summary: 'IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008]'