Human ITGA7 activation kit by CRISPRa

CAT#: GA102469

ITGA7 CRISPRa kit - CRISPR gene activation of human integrin subunit alpha 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ITGA7
• Locus ID: 3679
• Kit Components:

  GA102469G1, ITGA7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102469G2, ITGA7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102469G3, ITGA7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001144996, NM_001144997, NM_002206, NM_001367993, NM_001367994
• Synonyms: FLJ25220
• Summary: 'The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2009]'