Human CD11d (ITGAD) activation kit by CRISPRa

CAT#: GA102471

ITGAD CRISPRa kit - CRISPR gene activation of human integrin subunit alpha D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ITGAD
• Locus ID: 3681
• Kit Components:

  GA102471G1, CD11d gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102471G2, CD11d gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102471G3, CD11d gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001318185, NM_005353
• Synonyms: ADB2; CD11D
• Summary: 'This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]'