Human STT3A activation kit by CRISPRa

CAT#: GA102491

STT3A CRISPRa kit - CRISPR gene activation of human STT3 oligosaccharyltransferase complex catalytic subunit A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: STT3A
• Locus ID: 3703
• Kit Components:

  GA102491G1, STT3A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102491G2, STT3A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102491G3, STT3A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278503, NM_001278504, NM_002219, NM_152713
• Synonyms: ITM1; STT3-A; TMC
• Summary: 'The protein encoded by this gene is a catalytic subunit of the N-oligosaccharyltransferase (OST) complex, which functions in the endoplasmic reticulum to transfer glycan chains to asparagine residues of target proteins. A separate complex containing a similar catalytic subunit with an overlapping function also exists. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]'