Human ITPKB activation kit by CRISPRa

CAT#: GA102495

ITPKB CRISPRa kit - CRISPR gene activation of human inositol-trisphosphate 3-kinase B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ITPKB
• Locus ID: 3707
• Kit Components:

  GA102495G1, ITPKB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102495G2, ITPKB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102495G3, ITPKB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002221
• Synonyms: IP3-3KB; IP3K; IP3K-B; IP3KB; PIG37
• Summary: 'The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008]'