Human gamma Catenin (JUP) activation kit by CRISPRa

CAT#: GA102509

JUP CRISPRa kit - CRISPR gene activation of human junction plakoglobin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: JUP
• Locus ID: 3728
• Kit Components:

  GA102509G1, gamma Catenin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102509G2, gamma Catenin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102509G3, gamma Catenin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002230, NM_021991, NM_001352773, NM_001352774, NM_001352775, NM_001352776, NM_001352777
• Synonyms: ARVD12; CTNNG; DP3; DPIII; PDGB; PKGB
• Summary: 'This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]'