Human KCNG1 activation kit by CRISPRa

CAT#: GA102531

KCNG1 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel modifier subfamily G member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNG1
• Locus ID: 3755
• Kit Components:

  GA102531G1, KCNG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102531G2, KCNG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102531G3, KCNG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002237, NM_172318
• Synonyms: K13; KCNG; kH2; KV6.1
• Summary: 'Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Multiple alternatively spliced transcript variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008]'