Human KCNJ5 activation kit by CRISPRa

CAT#: GA102538

KCNJ5 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily J member 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNJ5
• Locus ID: 3762
• Kit Components:

  GA102538G1, KCNJ5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102538G2, KCNJ5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102538G3, KCNJ5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000890, NM_001354169
• Synonyms: CIR; GIRK4; KATP1; KIR3.4; LQT13
• Summary: 'This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas. [provided by RefSeq, Aug 2017]'