Human Kir2.2 (KCNJ12) activation kit by CRISPRa

CAT#: GA102544

KCNJ12 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily J member 12

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNJ12
• Locus ID: 3768
• Kit Components:

  GA102544G1, Kir2.2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102544G2, Kir2.2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102544G3, Kir2.2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021012
• Synonyms: hIRK; hIRK1; hkir2.2x; IRK-2; IRK2; kcnj12x; KCNJN1; Kir2.2; Kir2.2v
• Summary: 'This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]'