Human Transportin 1 (TNPO1) activation kit by CRISPRa

CAT#: GA102606

TNPO1 CRISPRa kit - CRISPR gene activation of human transportin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TNPO1
• Locus ID: 3842
• Kit Components:

  GA102606G1, TNPO1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA102606G2, TNPO1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA102606G3, TNPO1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002270, NM_153188, NM_001364292, NM_001364295, NM_001364296, NM_001364293, NM_001364294
• Synonyms: IPO2; KPNB2; MIP; MIP1; TRN
• Summary: This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in several transcript variants encoding different proteins. [provided by RefSeq, Jun 2018]