Human Cytokeratin 3 (KRT3) activation kit by CRISPRa

CAT#: GA102612

KRT3 CRISPRa kit - CRISPR gene activation of human keratin 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KRT3
• Locus ID: 3850
• Kit Components:

  GA102612G1, Cytokeratin 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102612G2, Cytokeratin 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102612G3, Cytokeratin 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_057088
• Synonyms: CK3; K3
• Summary: 'The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]'