Human Cytokeratin 8 (KRT8) activation kit by CRISPRa

CAT#: GA102618

KRT8 CRISPRa kit - CRISPR gene activation of human keratin 8

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

Product Images

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol KRT8
Locus ID 3856
Kit Components

GA102618G1, Cytokeratin 8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102618G2, Cytokeratin 8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102618G3, Cytokeratin 8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001256282, NM_001256293, NM_002273, NR_045962
Synonyms CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
Summary 'This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.