Human KRT84 activation kit by CRISPRa

CAT#: GA102638

KRT84 CRISPRa kit - CRISPR gene activation of human keratin 84

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KRT84
• Locus ID: 3890
• Kit Components:

  GA102638G1, KRT84 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102638G2, KRT84 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102638G3, KRT84 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_033045
• Synonyms: HB4; KRTHB4
• Summary: 'The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin is contained primarily in the filiform tongue papilla, among other hair keratins. [provided by RefSeq, Jul 2008]'