Human alpha Lactalbumin (LALBA) activation kit by CRISPRa

CAT#: GA102648

LALBA CRISPRa kit - CRISPR gene activation of human lactalbumin alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LALBA
• Locus ID: 3906
• Kit Components:

  GA102648G1, alpha Lactalbumin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102648G2, alpha Lactalbumin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102648G3, alpha Lactalbumin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002289
• Synonyms: LYZG
• Summary: 'This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008]'